Mechanisms of Exfoliation
نویسنده
چکیده
THE NORMAL EXFOLIATION PROCESS Exfoliation occurs naturally as outworn stratum corneum cells detach and are removed from the skin’s surface. Replacement of stratum corneum cells occurs by a self-renewal process as epidermal cells move upward from the basal layer, the stratum basalis, and through the subsequent two layers, the stratum spinosum and stratum granulosum, to reach the stratum corneum. This process requires about four weeks, although it can be prolonged in aging and other skin conditions. Normal desquamation occurs invisibly as single corneocytes, or very small aggregates of them, detach from the skin’s surface and are shed.
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